A 52-year-old mother who took cannabis oil to battle her terminal cancer has been given the all-clear by doctors.
Joy Smith was told she would only have six weeks to live when she was diagnosed with incurable stomach and bowel cancer in August 2016.
In a desperate attempt to defy expectations, she began taking a cannabis oil that contained THC, which is illegal in the UK. She is believed to have bought it online, the MailOnline reported,
And after a rollercoaster two years, she found out on Monday morning that she was cancer-free and would no longer have to have chemotherapy.
Ms Smith, from Coventry, said: "I am going to party for the rest of my life. I have got to be the only person in the world who has survived this.
"I keep pinching myself to see if this is real. I am being monitored every three months, but other than that I have no more treatment planned."
Ms Smith was told that she would have little longer than a month left to live unless she started chemotherapy to buy her more time.
She started having treatment every two weeks for three days, but had to have the line that delivered her chemotherapy taken out after she developed sepsis.
Ms Smith was unaware her friends had been researching an alternative cancer cure online until she was handed a cannabis-based tablet out of the blue.
She admitted that she didn't want to take it at first because she 'didn't know what it was' - but did so anyway in the hope of a cure.
The effects of THC - the compound that causes the 'high' - left her feeling 'drunk', Ms Smith claimed as she struggled to speak and 'words just slurred out'.
Ms Smith then started researching cannabis oil online and discovered it had worked for other sufferers - even though scientists are dubious.
After taking regular doses of cannabis oil containing THC, which is currently illegal in the UK, her inoperable tumours almost completely disappeared.
Ms Smith spoke about her battle against the cancer with the oil in March, when scans showed just a small amount of the disease left in her stomach.
She was hopeful then that the cancer would completely disappear with continued cannabis oil use.
And Ms Smith said she hadn't stopped smiling since her appointment with her consultant on Monday, and said the news has yet to sink in.
Ms Smith has received thousands of messages from fellow sufferers desperate to know more about her miracle cure, which has left doctors stunned.
She said: "I am just so happy. This is all down to the cannabis oil. I shouldn't be here, but I am.
"My daughter is in Australia at the minute and when I told her she thought I was lying.
"Everyone around me has been amazing, I have an army behind me and they're all so happy."
The legal status of cannabis oil in the UK has confused thousands after a landmark ruling that CBD, a compound in the drug, can be sold as a medicine with the correct licence. It is sold over-the-counter in Holland & Barrett. However, cannabis oil, which contains THC, is strictly illegal.
Cannabis oil and CBD oil is usually bottled with a dropper - but can also come in the form of chewing gum, soap or as a vape oil for e-cigarettes.
Both have been reported to help people with epilepsy, rheumatism, migraines, psoriasis, acne, multiple sclerosis and depression.
Cannabis oil is not available legally in the UK but can be sourced online. Ms Smith said the people contacting her are desperate to know how to get hold of it themselves.
Although she can't supply the oil herself, she tries to help in other ways. Ms Smith is writing a book about her journey so far and is determined to get it legalised.
She said: "I have got to get it legalised. I am so happy, happier than I have ever been. I just keep sharing the petition and hope it will make a difference.
"I believe my reason for being here is to help everyone else. Unless you have been faced with death you don't know."
Ms Smith is now looking forward to her life going back to normal. She said she will have her hair grow back after the long period of treatment.
She said: "I haven't had chemo for eight weeks, and four weeks ago was my last cancer treatment.
"I will have hair growing back, my nails will be strong. It just hasn't sunk in yet.
"I have to thank all the nurses and the doctors at University Hospitals Coventry and Warwickshire, they've been amazing and especially, Dr Sohgi.
"They have been the best for me, even though I have defied all their science."
A few days after learning she had nearly beaten the disease in March, Ms Smith discovered she won a competition she entered while 'high'.
After ticking everything off her bucket list after she received the terminal diagnosis, she was unsure how to spend her £84,000 prize money.
Ms Smith has started a petition to make cannabis oil legal in the UK for medical use, which has attracted more than 17,000 signatures.
CAN CANNABIS OIL CURE CANCER?
A mother-of-two claimed in February that she has cured her aggressive breast cancer by taking one drop of cannabis oil containing THC every day.
Dee Mani, 44, refused chemotherapy when she was diagnosed with triple negative breast cancer - deemed the deadliest form - and instead opted to try the oil, which is illegal in the UK.
Doctors gave her the all-clear just five months after she opted for the oil.
Despite her claims that it has cured her of cancer, there is no proof cannabis, or any of its compounds, can treat cancer in humans as research showing the drug's anti-tumour effects have been in petri dishes and on mice.
Dr Kat Arney, from Cancer Research UK, said that while study findings have been promising, cancer patients should not get their hopes up.
She previously said: "We know that cannabinoids can have a range of different effects on cancer cells grown in the lab and animal tumours.
"But at the moment there isn't good evidence from clinical trials to prove that they can safely and effectively treat cancer in patients."
Preclinical studies of cannabinoids have investigated the following
One study in mice and rats suggested that cannabinoids may have a protective effect against the development of certain types of tumors. During this 2-year study, groups of mice and rats were given various doses of THC by gavage. A dose-related decrease in the incidence of hepatic adenoma tumors and hepatocellular carcinoma (HCC) was observed in the mice. Decreased incidences of benign tumors (polyps and adenomas) in other organs (mammary gland, uterus, pituitary, testis, and pancreas) were also noted in the rats. In another study, delta-9-THC, delta-8-THC, and cannabinol were found to inhibit the growth of Lewis lungadenocarcinoma cells in vitro and in vivo . In addition, other tumors have been shown to be sensitive to cannabinoid-induced growth inhibition.[5-8]
Cannabinoids may cause antitumor effects by various mechanisms, including induction of cell death, inhibition of cell growth, and inhibition of tumor angiogenesis invasion and metastasis.[9-12] Two reviews summarize the molecular mechanisms of action of cannabinoids as antitumor agents.[13,14] Cannabinoids appear to kill tumor cells but do not affect their nontransformed counterparts and may even protect them from cell death. For example, these compounds have been shown to induce apoptosis in glioma cells in culture and induce regression of glioma tumors in mice and rats, while they protect normal glial cells of astroglial and oligodendroglial lineages from apoptosis mediated by the CB1 receptor.
The effects of delta-9-THC and a synthetic agonist of the CB2 receptor were investigated in HCC. Both agents reduced the viability of HCC cells in vitro and demonstrated antitumor effects in HCC subcutaneousxenografts in nude mice. The investigations documented that the anti-HCC effects are mediated by way of the CB2 receptor. Similar to findings in glioma cells, the cannabinoids were shown to trigger cell death through stimulation of an endoplasmic reticulum stress pathway that activates autophagy and promotes apoptosis. Other investigations have confirmed that CB1 and CB2 receptors may be potential targets in non-small cell lung carcinoma  and breast cancer.
An in vitro study of the effect of CBD on programmed cell death in breast cancer cell lines found that CBD induced programmed cell death, independent of the CB1, CB2, or vanilloid receptors. CBD inhibited the survival of both estrogen receptor–positive and estrogen receptor–negative breast cancer cell lines, inducing apoptosis in a concentration-dependent manner while having little effect on nontumorigenic mammary cells. Other studies have also shown the antitumor effect of cannabinoids (i.e., CBD and THC) in preclinical models of breast cancer.[19,20]
CBD has also been demonstrated to exert a chemopreventive effect in a mouse model of colon cancer. In this experimental system, azoxymethane increased premalignant and malignant lesions in the mouse colon. Animals treated with azoxymethane and CBD concurrently were protected from developing premalignant and malignant lesions. In in vitro experiments involving colorectal cancer cell lines, the investigators found that CBD protected DNA from oxidative damage, increased endocannabinoid levels, and reduced cell proliferation. In a subsequent study, the investigators found that the antiproliferative effect of CBD was counteracted by selective CB1 but not CB2 receptor antagonists, suggesting an involvement of CB1 receptors.
Another investigation into the antitumor effects of CBD examined the role of intercellular adhesion molecule-1 (ICAM-1). ICAM-1 expression has been reported to be negatively correlated with cancer metastasis. In lung cancer cell lines, CBD upregulated ICAM-1, leading to decreased cancer cell invasiveness.
In an in vivo model using severe combined immunodeficient mice, subcutaneous tumors were generated by inoculating the animals with cells from human non-small cell lung carcinoma cell lines. Tumor growth was inhibited by 60% in THC-treated mice compared with vehicle-treated control mice. Tumor specimens revealed that THC had antiangiogenic and antiproliferative effects. However, research with immunocompetent murine tumor models has demonstrated immunosuppression and enhanced tumor growth in mice treated with THC.[24,25]
In addition, both plant-derived and endogenous cannabinoids have been studied for anti-inflammatory effects. A mouse study demonstrated that endogenous cannabinoid system signaling is likely to provide intrinsic protection against colonic inflammation. As a result, a hypothesis that phytocannabinoids and endocannabinoids may be useful in the risk reduction and treatment of colorectal cancer has been developed.[27-30]
CBD may also enhance uptake of cytotoxic drugs into malignant cells. Activation of the transient receptor potential vanilloid type 2 (TRPV2) has been shown to inhibit proliferation of human glioblastoma multiformecells and overcome resistance to the chemotherapy agent carmustine.  One study showed that coadministration of THC and CBD over single-agent usage had greater antiproliferative activity in an in vitrostudy with multiple human glioblastoma multiforme cell lines. In an in vitro model, CBD increased TRPV2 activation and increased uptake of cytotoxic drugs, leading to apoptosis of glioma cells without affecting normal human astrocytes. This suggests that coadministration of CBD with cytotoxic agents may increase drug uptake and potentiate cell death in human glioma cells. Also, CBD together with THC may enhance the antitumor activity of classic chemotherapeutic drugs such as temozolomide in some mouse models of cancer.[13,33] A meta-analysis of 34 in vitro and in vivo studies of cannabinoids in glioma reported that all but one study confirmed that cannabinoids selectively kill tumor cells.